Visual Signs and Symptoms of Parkinson's Disease
13/08/10
Parkinson’s disease (PD) is the commonest neurodegenerative disorder in which the patient exhibits the symptoms of ‘parkinsonism’, viz., a range of problems involving movement, most typically manifest in PD itself, but also seen in closely related disorders such as progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and to some extent in dementia with Lewy bodies (DLB). It is a common disease throughout the world although less prevalent in China, Japan and in the Afro-Caribbean population. On average, the disease is believed to aect 1/750 of the population and calculated on this basis, there would be more than 100,000 cases in the UK. The prevalence of PD increases with age reaching a peak in the 7th decade of life after which it declines. Under 40 years of age, the prevalence in males (28/100,000)
is greater than in females (15/100,000) but this trend is reversed in the 7th and 8th decades (females 645-830/100,000; males 465-736/100,000).
There are two aspects of PD of particular interest to optometrists. First, PD patients can develop a range of visual problems including those aecting eye movements, pupillary function, and complex visual
functions involving the ability to judge distance or make out the shape of an object. Second, the symptoms of PD can be treated successfully
using a variety of drugs, some of which have significant ocular adverse reactions (OAR). This article describes the general features of PD, the
dopamine neurotransmitter system and its relevance to eye symptoms, the visual symptoms reported in PD, and the OAR that have been reported.
Richard Armstrong
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